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Synthesis and biological activity of 4-amino-3-chloro-1H-pyrrole-2,5-diones
4-Amino-3-chloro-1H-pyrrole-2,5-dione derivatives were designed and synthesized as potential tyrosine kinase inhibitors. One of them has been shown to inhibit growth of cancer cell lines and in vivo tumors. To determine the impact of side groups on biological activity the ability of different 4-amin...
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Pubblicato in: | In Silico Pharmacol |
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Autori principali: | , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Springer Berlin Heidelberg
2019
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6458214/ https://ncbi.nlm.nih.gov/pubmed/31032168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40203-019-0051-2 |
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