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Synthesis and biological activity of 4-amino-3-chloro-1H-pyrrole-2,5-diones
4-Amino-3-chloro-1H-pyrrole-2,5-dione derivatives were designed and synthesized as potential tyrosine kinase inhibitors. One of them has been shown to inhibit growth of cancer cell lines and in vivo tumors. To determine the impact of side groups on biological activity the ability of different 4-amin...
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| Publicado no: | In Silico Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6458214/ https://ncbi.nlm.nih.gov/pubmed/31032168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40203-019-0051-2 |
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