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GABARAPs dysfunction by autophagy deficiency in adolescent brain impairs GABA(A) receptor trafficking and social behavior

Dysfunctional mTOR signaling is associated with the pathogenesis of neurodevelopmental and neuropsychiatric disorders. However, it is unclear what molecular mechanisms and pathogenic mediators are involved and whether mTOR-regulated autophagy continues to be crucial beyond neurodevelopment. Here, we...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Adv
मुख्य लेखकों: Hui, Kelvin K., Takashima, Noriko, Watanabe, Akiko, Chater, Thomas E., Matsukawa, Hiroshi, Nekooki-Machida, Yoko, Nilsson, Per, Endo, Ryo, Goda, Yukiko, Saido, Takaomi C., Yoshikawa, Takeo, Tanaka, Motomasa
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Association for the Advancement of Science 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457945/
https://ncbi.nlm.nih.gov/pubmed/30989111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau8237
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