GABARAPs dysfunction by autophagy deficiency in adolescent brain impairs GABA(A) receptor trafficking and social behavior

Dysfunctional mTOR signaling is associated with the pathogenesis of neurodevelopmental and neuropsychiatric disorders. However, it is unclear what molecular mechanisms and pathogenic mediators are involved and whether mTOR-regulated autophagy continues to be crucial beyond neurodevelopment. Here, we...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Adv
Κύριοι συγγραφείς: Hui, Kelvin K., Takashima, Noriko, Watanabe, Akiko, Chater, Thomas E., Matsukawa, Hiroshi, Nekooki-Machida, Yoko, Nilsson, Per, Endo, Ryo, Goda, Yukiko, Saido, Takaomi C., Yoshikawa, Takeo, Tanaka, Motomasa
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Association for the Advancement of Science 2019
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457945/
https://ncbi.nlm.nih.gov/pubmed/30989111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau8237
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