TGF-β Signalling is Suppressed under Pro-Hypertrophic Conditions in MSC Chondrogenesis Due to TGF-β Receptor Downregulation

BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) become hypertrophic in long term despite chondrogenic differentiation following the pathway of growth plate chondrocytes. This terminal differentiation leads to phenotypically unstable cartilage and was mirrored in vitro by addition of hypertr...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Int J Stem Cells
Autors principals: Pfeifer, Christian G., Karl, Alexandra, Kerschbaum, Maximilian, Berner, Arne, Lang, Siegmund, Schupfner, Rupert, Koch, Matthias, Angele, Peter, Nerlich, Michael, Mueller, Michael B.
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Stem Cell Research 2019
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457698/
https://ncbi.nlm.nih.gov/pubmed/30836731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc18088
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars