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Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation
Diacylglycerol kinases (DGKs) are a family of enzymes that convert diacylglycerol (DAG) into phosphatidic acid (PA). The ζ isoform of DGK (DGKζ) has been reported to inhibit T-cell responsiveness by downregulating intracellular levels of DAG. However, its role in platelet function remains undefined....
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| Vydáno v: | Blood Adv |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6457232/ https://ncbi.nlm.nih.gov/pubmed/30967391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018026328 |
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