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FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2

Although humans with X-linked hypophosphatemia (XLH) and the Hyp mouse, a murine homolog of XLH, are known to develop degenerative joint disease, the exact mechanism that drives the osteoarthritis (OA) phenotype remains unclear. Mice that overexpress high-molecular-weight fibroblast growth factor (F...

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Опубликовано в: :Endocrinology
Главные авторы: Meo Burt, Patience, Xiao, Liping, Hurley, Marja M
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457004/
https://ncbi.nlm.nih.gov/pubmed/29718273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00184
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