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Nuclear FGF2 Isoforms Inhibit Bone Marrow Stromal Cell Mineralization through FGF23/FGFR/MAPK In Vitro

Fibroblast growth factor 23 (FGF23) is responsible for phosphate wasting and the phenotypic changes observed in human diseases such as X-Linked Hypophosphatemia (XLH). Targeted over-expression of nuclear high molecular weight fibroblast growth factor 2 isoforms (HMW isoforms) in osteoblasts resulted...

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Detalhes bibliográficos
Main Authors: Xiao, Liping, Esliger, Alycia, Hurley, Marja M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519956/
https://ncbi.nlm.nih.gov/pubmed/22836867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1721
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