Inhibition of FGFR Signaling Partially Rescues Osteoarthritis in Mice Overexpressing High Molecular Weight FGF2 Isoforms

Fibroblast growth factor 2 (FGF2) and fibroblast growth factor receptors (FGFRs) are key regulatory factors in osteoarthritis (OA). HMWTg mice overexpress the high molecular weight FGF2 isoforms (HMWFGF2) in osteoblast lineage and phenocopy both Hyp mice (which overexpress the HMWFGF2 isoforms in os...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Endocrinology
Main Authors: Xiao, Liping, Williams, Donyell, Hurley, Marja M
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959088/
https://ncbi.nlm.nih.gov/pubmed/31901095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqz016
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