Inhibition of FGFR Signaling Partially Rescues Osteoarthritis in Mice Overexpressing High Molecular Weight FGF2 Isoforms

Fibroblast growth factor 2 (FGF2) and fibroblast growth factor receptors (FGFRs) are key regulatory factors in osteoarthritis (OA). HMWTg mice overexpress the high molecular weight FGF2 isoforms (HMWFGF2) in osteoblast lineage and phenocopy both Hyp mice (which overexpress the HMWFGF2 isoforms in os...

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Detaylı Bibliyografya
Yayımlandı:Endocrinology
Asıl Yazarlar: Xiao, Liping, Williams, Donyell, Hurley, Marja M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959088/
https://ncbi.nlm.nih.gov/pubmed/31901095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqz016
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