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FGF2 High Molecular Weight Isoforms Contribute to Osteoarthropathy in Male Mice

Humans with X-linked hypophosphatemia (XLH) and Hyp mice, the murine homolog of the disease, develop severe osteoarthropathy and the precise factors that contribute to this joint degeneration remain largely unknown. Fibroblast growth factor 2 (FGF2) is a key regulatory growth factor in osteoarthriti...

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Publicat a:Endocrinology
Autors principals: Meo Burt, Patience, Xiao, Liping, Dealy, Caroline, Fisher, Melanie C., Hurley, Marja M.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133359/
https://ncbi.nlm.nih.gov/pubmed/27732085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1548
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