FGF2-FGFR1 signaling regulates release of Leukemia-Protective exosomes from bone marrow stromal cells

Protective signaling from the leukemia microenvironment leads to leukemia cell persistence, development of resistance, and disease relapse. Here, we demonstrate that fibroblast growth factor 2 (FGF2) from bone marrow stromal cells is secreted in exosomes, which are subsequently endocytosed by leukem...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Javidi-Sharifi, Nathalie, Martinez, Jacqueline, English, Isabel, Joshi, Sunil K, Scopim-Ribeiro, Renata, Viola, Shelton K, Edwards, David K, Agarwal, Anupriya, Lopez, Claudia, Jorgens, Danielle, Tyner, Jeffrey W, Druker, Brian J, Traer, Elie
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363389/
https://ncbi.nlm.nih.gov/pubmed/30720426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40033
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados