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Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations
Development of resistance to kinase inhibitors remains a clinical challenge. Kinase domain mutations are a common mechanism of resistance in chronic myeloid leukemia (CML), yet the mechanism of resistance in the absence of mutations remains unclear. We tested proteins from the bone marrow microenvir...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945862/ https://ncbi.nlm.nih.gov/pubmed/24408322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-518381 |
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