Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations

Development of resistance to kinase inhibitors remains a clinical challenge. Kinase domain mutations are a common mechanism of resistance in chronic myeloid leukemia (CML), yet the mechanism of resistance in the absence of mutations remains unclear. We tested proteins from the bone marrow microenvir...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Traer, Elie, Javidi-Sharifi, Nathalie, Agarwal, Anupriya, Dunlap, Jennifer, English, Isabel, Martinez, Jacqueline, Tyner, Jeffrey W., Wong, Melissa, Druker, Brian J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945862/
https://ncbi.nlm.nih.gov/pubmed/24408322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-518381
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker