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Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML
Sequestration in the bone marrow niche may allow leukemic stem cells to evade exposure to drugs. Because the CXCR4/SDF-1 axis is an important mechanism of leukemic stem cell interaction with marrow stroma, we tested whether plerixafor, an antagonist of CXCR4, may dislodge chronic myeloid leukemia (C...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3460687/ https://ncbi.nlm.nih.gov/pubmed/22889761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-355396 |
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