Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

Melanoma patients carry a high risk of developing brain metastases, and improvements in survival are still measured in weeks or months. Durable disease control within the brain is impeded by poor drug penetration across the blood-brain barrier, as well as intrinsic and acquired drug resistance. Augm...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Acta Neuropathol Commun
Päätekijät: Sundstrøm, Terje, Prestegarden, Lars, Azuaje, Francisco, Aasen, Synnøve Nymark, Røsland, Gro Vatne, Varughese, Jobin K., Bahador, Marzieh, Bernatz, Simon, Braun, Yannick, Harter, Patrick N., Skaftnesmo, Kai Ove, Ingham, Elizabeth S., Mahakian, Lisa M., Tam, Sarah, Tepper, Clifford G., Petersen, Kjell, Ferrara, Katherine W., Tronstad, Karl Johan, Lund-Johansen, Morten, Beschorner, Rudi, Bjerkvig, Rolf, Thorsen, Frits
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2019
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456988/
https://ncbi.nlm.nih.gov/pubmed/30971321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0712-8
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