Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

Melanoma patients carry a high risk of developing brain metastases, and improvements in survival are still measured in weeks or months. Durable disease control within the brain is impeded by poor drug penetration across the blood-brain barrier, as well as intrinsic and acquired drug resistance. Augm...

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Detaylı Bibliyografya
Yayımlandı:Acta Neuropathol Commun
Asıl Yazarlar: Sundstrøm, Terje, Prestegarden, Lars, Azuaje, Francisco, Aasen, Synnøve Nymark, Røsland, Gro Vatne, Varughese, Jobin K., Bahador, Marzieh, Bernatz, Simon, Braun, Yannick, Harter, Patrick N., Skaftnesmo, Kai Ove, Ingham, Elizabeth S., Mahakian, Lisa M., Tam, Sarah, Tepper, Clifford G., Petersen, Kjell, Ferrara, Katherine W., Tronstad, Karl Johan, Lund-Johansen, Morten, Beschorner, Rudi, Bjerkvig, Rolf, Thorsen, Frits
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456988/
https://ncbi.nlm.nih.gov/pubmed/30971321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0712-8
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