ロード中...
AR Signaling in Prostate Cancer Regulates a Feed-Forward Mechanism of Androgen Synthesis by Way of HSD3B1 Upregulation
3βHSD1 enzymatic activity is essential for synthesis of potent androgens from adrenal precursor steroids in prostate cancer. A germline variant in HSD3B1, the gene that encodes 3βHSD1, encodes for a stable enzyme, regulates adrenal androgen dependence, and is a predictive biomarker of poor clinical...
保存先:
| 出版年: | Endocrinology |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Endocrine Society
2018
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6456955/ https://ncbi.nlm.nih.gov/pubmed/29850791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00283 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|