Structures of class Id ribonucleotide reductase catalytic subunits reveal a minimal architecture for deoxynucleotide biosynthesis

Class I ribonucleotide reductases (RNRs) share a common mechanism of nucleotide reduction in a catalytic α subunit. All RNRs initiate catalysis with a thiyl radical, generated in class I enzymes by a metallocofactor in a separate β subunit. Class Id RNRs use a simple mechanism of cofactor activation...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Rose, Hannah R., Maggiolo, Ailiena O., McBride, Molly J., Palowitch, Gavin M., Pandelia, Maria-Eirini, Davis, Katherine M., Yennawar, Neela H., Boal, Amie K.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456427/
https://ncbi.nlm.nih.gov/pubmed/30855138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01252
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares