Lanean...
The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2B(Intron5)-associated toxicity in animal models of frontotemporal dementia
Frontotemporal dementia (FTD) is one of the most prevalent forms of early-onset dementia. However, the pathological mechanisms driving neuronal atrophy in FTD remain poorly understood. Here we identify a conserved role for the novel pro-apoptotic protein plenty of SH3s (POSH)/SH3 domain containing r...
Gorde:
| Argitaratua izan da: | Hum Mol Genet |
|---|---|
| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2018
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6454437/ https://ncbi.nlm.nih.gov/pubmed/29432529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy048 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|