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The Role of CHMP2B(Intron5) in Autophagy and Frontotemporal Dementia

Charged multivesicular body protein 2B (CHMP2B) – a component of the endosomal complex required for transport-III (ESCRT-III) – is responsible for the vital membrane deformation functions in autophagy and endolysosomal trafficking. A dominant mutation in CHMP2B (CHMP2B(Intron5)) is associated with a...

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Publicat a:Brain Res
Autors principals: Krasniak, Christopher S., Ahmad, S. Tariq
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018243/
https://ncbi.nlm.nih.gov/pubmed/26972529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.02.051
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