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The Role of CHMP2B(Intron5) in Autophagy and Frontotemporal Dementia
Charged multivesicular body protein 2B (CHMP2B) – a component of the endosomal complex required for transport-III (ESCRT-III) – is responsible for the vital membrane deformation functions in autophagy and endolysosomal trafficking. A dominant mutation in CHMP2B (CHMP2B(Intron5)) is associated with a...
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| Published in: | Brain Res |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5018243/ https://ncbi.nlm.nih.gov/pubmed/26972529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.02.051 |
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