Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury

Introduction: Elevated levels of mitochondrial reactive oxygen species (ROS) contribute to the development of numerous cardiovascular diseases. TERT, the catalytic subunit of telomerase, has been shown to translocate to mitochondria to suppress ROS while promoting ATP production. Acute overexpressio...

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Detalles Bibliográficos
Publicado en:Front Cardiovasc Med
Main Authors: Ait-Aissa, Karima, Heisner, James S., Norwood Toro, Laura E., Bruemmer, Dennis, Doyon, Genevieve, Harmann, Leanne, Geurts, Aron, Camara, Amadou K. S., Beyer, Andreas M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Cardiovascular Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454001/
https://ncbi.nlm.nih.gov/pubmed/31001540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2019.00031
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