Brain-transportable dipeptides across the blood-brain barrier in mice

Apart from nutrients required for the brain, there has been no report that naturally occurring peptides can cross the blood-brain barrier (BBB). The aim of this study was to identify the BBB-transportable peptides using in situ mouse perfusion experiments. Based on the structural features of Gly-N-m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tanaka, Mitsuru, Dohgu, Shinya, Komabayashi, Genki, Kiyohara, Hayato, Takata, Fuyuko, Kataoka, Yasufumi, Nirasawa, Takashi, Maebuchi, Motohiro, Matsui, Toshiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6453885/
https://ncbi.nlm.nih.gov/pubmed/30962462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42099-9
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