Tumor Necrosis Factor-α Mediates the Blood–Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells

The present study was designed to elucidate the involvement of tumor necrosis factor-α (TNF-α) release from activated microglia in the induction of blood–brain barrier (BBB) dysfunction in an in vitro co-culture system with mouse brain capillary endothelial cells (MBEC4) and microglia. Lipopolysacch...

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Bibliografiske detaljer

Principais autores:	Tsuyoshi Nishioku, Junichi Matsumoto, Shinya Dohgu, Noriko Sumi, Kenji Miyao, Fuyuko Takata, Hideki Shuto, Atsushi Yamauchi, Yasufumi Kataoka
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2010-01-01
Serier:	Journal of Pharmacological Sciences
Online adgang:	http://www.sciencedirect.com/science/article/pii/S1347861319310291
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