Contribution of thrombin-reactive brain pericytes to blood-brain barrier dysfunction in an in vivo mouse model of obesity-associated diabetes and an in vitro rat model

Diabetic complications are characterized by the dysfunction of pericytes located around microvascular endothelial cells. The blood–brain barrier (BBB) exhibits hyperpermeability with progression of diabetes. Therefore, brain pericytes at the BBB may be involved in diabetic complications of the centr...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Machida, Takashi, Takata, Fuyuko, Matsumoto, Junichi, Miyamura, Tomoyuki, Hirata, Ryosuke, Kimura, Ikuya, Kataoka, Yasufumi, Dohgu, Shinya, Yamauchi, Atsushi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425209/
https://ncbi.nlm.nih.gov/pubmed/28489922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177447
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