Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads

A total of 44 bis-aryl-monocyclic polyamines, monoaryl-monocyclic polyamines and their transition metal complexes were prepared, chemically characterized, and screened in vitro against the Leishmania donovani promastigotes, axenic amastigotes and intracellular amastigotes in THP1 cells. The IC(50) a...

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Detalhes bibliográficos
Publicado no:Polyhedron
Main Authors: Hubin, Timothy J., Walker, Ashlie N., Davilla, Dustin J., Freeman, TaRynn N. Carder, Epley, Brittany M., Hasley, Travis R., Amoyaw, Prince N. A., Jain, Surendra, Archibald, Stephen J., Prior, Timothy J., Krause, Jeanette A., Oliver, Allen G., Tekwani, Babu L., Khan, M. Omar F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452907/
https://ncbi.nlm.nih.gov/pubmed/30976133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.poly.2019.02.027
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