Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads

A total of 44 bis-aryl-monocyclic polyamines, monoaryl-monocyclic polyamines and their transition metal complexes were prepared, chemically characterized, and screened in vitro against the Leishmania donovani promastigotes, axenic amastigotes and intracellular amastigotes in THP1 cells. The IC(50) a...

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Bibliographic Details
Published in:Polyhedron
Main Authors: Hubin, Timothy J., Walker, Ashlie N., Davilla, Dustin J., Freeman, TaRynn N. Carder, Epley, Brittany M., Hasley, Travis R., Amoyaw, Prince N. A., Jain, Surendra, Archibald, Stephen J., Prior, Timothy J., Krause, Jeanette A., Oliver, Allen G., Tekwani, Babu L., Khan, M. Omar F.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452907/
https://ncbi.nlm.nih.gov/pubmed/30976133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.poly.2019.02.027
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