Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers

Substrate-binding proteins (SBPs) are associated with ATP-binding cassette importers and switch from an open to a closed conformation upon substrate binding, providing specificity for transport. We investigated the effect of substrates on the conformational dynamics of six SBPs and the impact on tra...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:eLife
Glavni autori: de Boer, Marijn, Gouridis, Giorgos, Vietrov, Ruslan, Begg, Stephanie L, Schuurman-Wolters, Gea K, Husada, Florence, Eleftheriadis, Nikolaos, Poolman, Bert, McDevitt, Christopher A, Cordes, Thorben
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Biochemistry and Chemical Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450668/
https://ncbi.nlm.nih.gov/pubmed/30900991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44652
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items