ABCE1 Controls Ribosome Recycling by an Asymmetric Dynamic Conformational Equilibrium

The twin-ATPase ABCE1 has a vital function in mRNA translation by recycling terminated or stalled ribosomes. As for other functionally distinct ATP-binding cassette (ABC) proteins, the mechanochemical coupling of ATP hydrolysis to conformational changes remains elusive. Here, we use an integrated bi...

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Udgivet i:Cell Rep
Main Authors: Gouridis, Giorgos, Hetzert, Bianca, Kiosze-Becker, Kristin, de Boer, Marijn, Heinemann, Holger, Nürenberg-Goloub, Elina, Cordes, Thorben, Tampé, Robert
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656783/
https://ncbi.nlm.nih.gov/pubmed/31315050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.052
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