HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules

All living organisms contain a unique class of molecular chaperones called 60 kDa heat shock proteins (HSP60 – also known as GroEL in bacteria). While some organisms contain more than one HSP60 or GroEL isoform, at least one isoform has always proven to be essential. Because of this, we have been in...

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Publicado en:Bioorg Med Chem Lett
Autores principales: Stevens, Mckayla, Abdeen, Sanofar, Salim, Nilshad, Ray, Anne-Marie, Washburn, Alex, Chitre, Siddhi, Sivinski, Jared, Park, Yangshin, Hoang, Quyen Q., Chapman, Eli, Johnson, Steven M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450568/
https://ncbi.nlm.nih.gov/pubmed/30852084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.02.028
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