Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib

The third-generation tyrosine kinase inhibitor (TKI) ponatinib has been associated with high rates of acute ischemic events. The pathophysiology responsible for these events is unknown. We hypothesized that ponatinib produces an endothelial angiopathy involving excessive endothelial-associated von W...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Latifi, Yllka, Moccetti, Federico, Wu, Melinda, Xie, Aris, Packwood, William, Qi, Yue, Ozawa, Koya, Shentu, Weihui, Brown, Eran, Shirai, Toshiaki, McCarty, Owen J., Ruggeri, Zaverio, Moslehi, Javid, Chen, Junmei, Druker, Brian J., López, Jose A., Lindner, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450432/
https://ncbi.nlm.nih.gov/pubmed/30692122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-10-881557
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados