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The DNase Activity of Kaposi’s Sarcoma-Associated Herpesvirus SOX Protein Serves an Important Role in Viral Genome Processing during Lytic Replication
The Kaposi's sarcoma-associated herpesvirus (KSHV) alkaline exonuclease SOX, encoded by open reading frame 37 (ORF37), is a bifunctional early-lytic-phase protein that possesses alkaline 5′-to-3′ DNase activity and promotes host shutoff at the mRNA level during productive lytic infection. While...
Tallennettuna:
| Julkaisussa: | J Virol |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450125/ https://ncbi.nlm.nih.gov/pubmed/30728255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01983-18 |
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