Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome

BCOR, encoding BCL-6 corepressor (BCOR), is X-linked and targeted by somatic mutations in various hematological malignancies including myelodysplastic syndrome (MDS). We previously reported that mice lacking Bcor exon 4 (Bcor(ΔE4/y)) in the hematopoietic compartment developed NOTCH-dependent acute T...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Tara, Shiro, Isshiki, Yusuke, Nakajima-Takagi, Yaeko, Oshima, Motohiko, Aoyama, Kazumasa, Tanaka, Tomoyuki, Shinoda, Daisuke, Koide, Shuhei, Saraya, Atsunori, Miyagi, Satoru, Manabe, Ichiro, Matsui, Hirotaka, Koseki, Haruhiko, Bardwell, Vivian J., Iwama, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450057/
https://ncbi.nlm.nih.gov/pubmed/30228234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-01-827964
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