Loss of Pcgf5 Affects Global H2A Monoubiquitination but Not the Function of Hematopoietic Stem and Progenitor Cells

Polycomb-group RING finger proteins (Pcgf1-Pcgf6) are components of Polycomb repressive complex 1 (PRC1)-related complexes that catalyze monoubiquitination of histone H2A at lysine 119 (H2AK119ub1), an epigenetic mark associated with repression of genes. Pcgf5 has been characterized as a component o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Si, Sha, Nakajima-Takagi, Yaeko, Aoyama, Kazumasa, Oshima, Motohiko, Saraya, Atsunori, Sugishita, Hiroki, Nakayama, Manabu, Ishikura, Tomoyuki, Koseki, Haruhiko, Iwama, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852895/
https://ncbi.nlm.nih.gov/pubmed/27136092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154561
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