Selective Restoration of Pomc Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network

Hypothalamic POMC deficiency leads to obesity and metabolic deficiencies, largely due to the loss of melanocortin peptides. However, POMC neurons in the arcuate nucleus (ARC) are comprised of glutamatergic and GABAergic subpopulations. The developmental program, relative proportion and function of t...

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Bibliografiska uppgifter
I publikationen:eNeuro
Huvudupphovsmän: Jones, Graham L., Wittmann, Gábor, Yokosawa, Eva B., Yu, Hui, Mercer, Aaron J., Lechan, Ronald M., Low, Malcolm J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2019
Ämnen:
New Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449166/
https://ncbi.nlm.nih.gov/pubmed/30957016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0400-18.2019
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