Selective Restoration of Pomc Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network

Hypothalamic POMC deficiency leads to obesity and metabolic deficiencies, largely due to the loss of melanocortin peptides. However, POMC neurons in the arcuate nucleus (ARC) are comprised of glutamatergic and GABAergic subpopulations. The developmental program, relative proportion and function of t...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Jones, Graham L., Wittmann, Gábor, Yokosawa, Eva B., Yu, Hui, Mercer, Aaron J., Lechan, Ronald M., Low, Malcolm J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449166/
https://ncbi.nlm.nih.gov/pubmed/30957016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0400-18.2019
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