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Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa

The permeability barrier of Gram-negative cell envelopes is the major obstacle in the discovery and development of new antibiotics. In Gram-negative bacteria, these difficulties are exacerbated by the synergistic interaction between two biochemically distinct phenomena, the low permeability of the o...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Cooper, Sarah J., Krishnamoorthy, Ganesh, Wolloscheck, David, Walker, John K., Rybenkov, Valentin V., Parks, Jerry M., Zgurskaya, Helen I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449051/
https://ncbi.nlm.nih.gov/pubmed/29756762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00036
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