Llwytho...

EFdA (4′-ethynyl-2-fluoro-2′-deoxyadenosine, MK-8591): A Novel HIV-1 Reverse Transcriptase Translocation Inhibitor

PURPOSE OF THE REVIEW: 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) is a nucleoside inhibitor of reverse transcriptase (NRTI) with a novel mechanism of action, unique structure, and amongst NRTIs, unparalleled anti-HIV-1 activity. We will summarize its structure and function, antiviral activity, res...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Opin HIV AIDS
Prif Awduron: Markowitz, Martin, Sarafianos, Stefan G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449048/
https://ncbi.nlm.nih.gov/pubmed/29697468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0000000000000467
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!