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EFdA (4′-ethynyl-2-fluoro-2′-deoxyadenosine, MK-8591): A Novel HIV-1 Reverse Transcriptase Translocation Inhibitor
PURPOSE OF THE REVIEW: 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) is a nucleoside inhibitor of reverse transcriptase (NRTI) with a novel mechanism of action, unique structure, and amongst NRTIs, unparalleled anti-HIV-1 activity. We will summarize its structure and function, antiviral activity, res...
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| Publicado no: | Curr Opin HIV AIDS |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6449048/ https://ncbi.nlm.nih.gov/pubmed/29697468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0000000000000467 |
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