ROS amplification drives mouse spermatogonial stem cell self-renewal

Reactive oxygen species (ROS) play critical roles in self-renewal division for various stem cell types. However, it remains unclear how ROS signals are integrated with self-renewal machinery. Here, we report that the MAPK14/MAPK7/BCL6B pathway creates a positive feedback loop to drive spermatogonial...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Morimoto, Hiroko, Kanastu-Shinohara, Mito, Ogonuki, Narumi, Kamimura, Satoshi, Ogura, Atsuo, Yabe-Nishimura, Chihiro, Mori, Yoshifumi, Morimoto, Takeshi, Watanabe, Satoshi, Otsu, Kinya, Yamamoto, Takuya, Shinohara, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448598/
https://ncbi.nlm.nih.gov/pubmed/30940732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900374
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