Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal

Myc plays critical roles in the self-renewal division of various stem cell types. In spermatogonial stem cells (SSCs), Myc controls SSC fate decisions because Myc overexpression induces enhanced self-renewal division, while depletion of Max, a Myc-binding partner, leads to meiotic induction. However...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Kanatsu-Shinohara, Mito, Tanaka, Takashi, Ogonuki, Narumi, Ogura, Atsuo, Morimoto, Hiroko, Cheng, Pei Feng, Eisenman, Robert N., Trumpp, Andreas, Shinohara, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204355/
https://ncbi.nlm.nih.gov/pubmed/28007786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.287045.116
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