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Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers
Emerging notion in carcinogenesis ascribes tumor initiation and aggressiveness to cancer stem cells (CSCs). Specifically, colorectal cancer (CRC) development was shown to be compatible with CSCs hypothesis. Mutations in p53 are highly frequent in CRC, and are known to facilitate tumor development an...
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| Publicat a: | Oncogene |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448595/ https://ncbi.nlm.nih.gov/pubmed/29343849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0060-8 |
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