Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

Emerging notion in carcinogenesis ascribes tumor initiation and aggressiveness to cancer stem cells (CSCs). Specifically, colorectal cancer (CRC) development was shown to be compatible with CSCs hypothesis. Mutations in p53 are highly frequent in CRC, and are known to facilitate tumor development an...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Solomon, Hilla, Dinowitz, Nathan, Pateras, loannis S., Cooks, Tomer, Shetzer, Yoav, Molchadsky, Alina, Charni, Meital, Rabani, Stav, Koifman, Gabriela, Tarcic, Ohad, Porat, Ziv, Kogan-Sakin, Ira, Goldfinger, Naomi, Oren, Moshe, Harris, Curtis C., Gorgoulis, Vassilis G., Rotter, Varda
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448595/
https://ncbi.nlm.nih.gov/pubmed/29343849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0060-8
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