Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers

Emerging notion in carcinogenesis ascribes tumor initiation and aggressiveness to cancer stem cells (CSCs). Specifically, colorectal cancer (CRC) development was shown to be compatible with CSCs hypothesis. Mutations in p53 are highly frequent in CRC, and are known to facilitate tumor development an...

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Publicado en:Oncogene
Main Authors: Solomon, Hilla, Dinowitz, Nathan, Pateras, loannis S., Cooks, Tomer, Shetzer, Yoav, Molchadsky, Alina, Charni, Meital, Rabani, Stav, Koifman, Gabriela, Tarcic, Ohad, Porat, Ziv, Kogan-Sakin, Ira, Goldfinger, Naomi, Oren, Moshe, Harris, Curtis C., Gorgoulis, Vassilis G., Rotter, Varda
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448595/
https://ncbi.nlm.nih.gov/pubmed/29343849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0060-8
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