Programmed cell death ligand 1 disruption by clustered regularly interspaced short palindromic repeats/Cas9‐genome editing promotes antitumor immunity and suppresses ovarian cancer progression

Programmed cell death ligand 1 (PD‐L1) on tumor cells suppresses anti‐tumor immunity and has an unfavorable prognostic impact in ovarian cancer patients. We herein report the pathophysiological and therapeutic impacts of PD‐L1 disruption in ovarian cancer. PD‐L1 was genetically disrupted in the muri...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Sci
Main Authors: Yahata, Tamaki, Mizoguchi, Mika, Kimura, Akihiko, Orimo, Takashi, Toujima, Saori, Kuninaka, Yumi, Nosaka, Mizuho, Ishida, Yuko, Sasaki, Izumi, Fukuda‐Ohta, Yuri, Hemmi, Hiroaki, Iwahashi, Naoyuki, Noguchi, Tomoko, Kaisho, Tsuneyasu, Kondo, Toshikazu, Ino, Kazuhiko
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2019
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447841/
https://ncbi.nlm.nih.gov/pubmed/30702189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13958
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