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GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice

The transcription factor GATA2 regulates normal hematopoiesis, particularly in‐ stem cell maintenance and myeloid differentiation. Various heteroallelic GATA2 gene mutations are associated with a variety of hematological neoplasms, including myelodysplastic syndromes and leukemias. Here, we report t...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Harada, Nobuhiko, Hasegawa, Atsushi, Hirano, Ikuo, Yamamoto, Masayuki, Shimizu, Ritsuko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447832/
https://ncbi.nlm.nih.gov/pubmed/30710465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13959
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