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GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice

The transcription factor GATA2 regulates normal hematopoiesis, particularly in‐ stem cell maintenance and myeloid differentiation. Various heteroallelic GATA2 gene mutations are associated with a variety of hematological neoplasms, including myelodysplastic syndromes and leukemias. Here, we report t...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Harada, Nobuhiko, Hasegawa, Atsushi, Hirano, Ikuo, Yamamoto, Masayuki, Shimizu, Ritsuko
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447832/
https://ncbi.nlm.nih.gov/pubmed/30710465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13959
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