Chargement en cours...

GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice

The transcription factor GATA2 regulates normal hematopoiesis, particularly in‐ stem cell maintenance and myeloid differentiation. Various heteroallelic GATA2 gene mutations are associated with a variety of hematological neoplasms, including myelodysplastic syndromes and leukemias. Here, we report t...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Harada, Nobuhiko, Hasegawa, Atsushi, Hirano, Ikuo, Yamamoto, Masayuki, Shimizu, Ritsuko
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447832/
https://ncbi.nlm.nih.gov/pubmed/30710465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13959
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!