UG4 Enhancer-Driven GATA-2 and Bone Morphogenetic Protein 4 Complementation Remedies the CAKUT Phenotype in Gata2 Hypomorphic Mutant Mice

During renal development, the proper emergence of the ureteric bud (UB) from the Wolffian duct is essential for formation of the urinary system. Previously, we showed that expression of transcription factor GATA-2 in the urogenital primordium was demarcated anteroposteriorly into two domains that we...

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Detalhes bibliográficos
Main Authors: Ainoya, Keiko, Moriguchi, Takashi, Ohmori, Shin'ya, Souma, Tomokazu, Takai, Jun, Morita, Masanobu, Chandler, Kelly J., Mortlock, Douglas P., Shimizu, Ritsuko, Engel, James Douglas, Lim, Kim-Chew, Yamamoto, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372261/
https://ncbi.nlm.nih.gov/pubmed/22493062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06699-11
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