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Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect

GATA3 is a zinc finger transcription factor that plays a crucial role in embryonic kidney development, while its precise functions in the adult kidney remain largely unexplored. Here, we demonstrate that GATA3 is specifically expressed in glomerular mesangial cells and plays a critical role in the m...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Moriguchi, Takashi, Yu, Lei, Otsuki, Akihito, Ainoya, Keiko, Lim, Kim-Chew, Yamamoto, Masayuki, Engel, James Douglas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985934/
https://ncbi.nlm.nih.gov/pubmed/27296697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00173-16
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