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Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect

GATA3 is a zinc finger transcription factor that plays a crucial role in embryonic kidney development, while its precise functions in the adult kidney remain largely unexplored. Here, we demonstrate that GATA3 is specifically expressed in glomerular mesangial cells and plays a critical role in the m...

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Publicado en:Mol Cell Biol
Autores principales: Moriguchi, Takashi, Yu, Lei, Otsuki, Akihito, Ainoya, Keiko, Lim, Kim-Chew, Yamamoto, Masayuki, Engel, James Douglas
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985934/
https://ncbi.nlm.nih.gov/pubmed/27296697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00173-16
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