A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression

Transcription factor GATA3 plays vital roles in inner ear development, while regulatory mechanisms controlling its inner ear-specific expression are undefined. We demonstrate that a cis-regulatory element lying 571 kb 3′ to the Gata3 gene directs inner ear-specific Gata3 expression, which we refer t...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Moriguchi, Takashi, Hoshino, Tomofumi, Rao, Arvind, Yu, Lei, Takai, Jun, Uemura, Satoshi, Ise, Kazue, Nakamura, Yasuhiro, Lim, Kim-Chew, Shimizu, Ritsuko, Yamamoto, Masayuki, Engel, James Douglas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189460/
https://ncbi.nlm.nih.gov/pubmed/30126893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00302-18
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