G-quadruplex dynamics contribute to regulation of mitochondrial gene expression

Single-stranded DNA or RNA sequences rich in guanine (G) can adopt non-canonical structures known as G-quadruplexes (G4). Mitochondrial DNA (mtDNA) sequences that are predicted to form G4 are enriched on the heavy-strand and have been associated with formation of deletion breakpoints. Increasing evi...

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Udgivet i:Sci Rep
Main Authors: Falabella, M., Kolesar, J. E., Wallace, C., de Jesus, D., Sun, L., Taguchi, Y. V., Wang, C., Wang, T., Xiang, I. M., Alder, J. K., Maheshan, R., Horne, W., Turek-Herman, J., Pagano, P. J., St. Croix, C. M., Sondheimer, N., Yatsunyk, L. A., Johnson, F. B., Kaufman, B. A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447596/
https://ncbi.nlm.nih.gov/pubmed/30944353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41464-y
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