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N‐methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexes

Guanine quadruplexes (GQ) are four‐stranded DNA structures formed by guanine‐rich DNA sequences. The formation of GQs inhibits cancer cell growth, although the detection of GQs in vivo has proven difficult, in part because of their structural diversity. The development of GQ‐selective fluorescent re...

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Détails bibliographiques
Auteurs principaux: Sabharwal, Navin C., Savikhin, Victoria, Turek‐Herman, Joshua R., Nicoludis, John M., Szalai, Veronika A., Yatsunyk, Liliya A.
Format: Artigo
Langue:Inglês
Publié: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163640/
https://ncbi.nlm.nih.gov/pubmed/24494857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12734
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